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Do menstrual products contain harmful substances?

This is the best evidence we could find. Comments warmly welcome! (please write andisheh.jahangir@womena.dk)



Concerns about harmful substances in menstrual products are common and frequently expressed in alarmist headlines in the media. Sometimes the concerns result in voluntary withdrawal of the product from the market such as one type of tampon by a famous company (Dudley et al., 2018; Rinkunas 2018). WoMena has assessed available evidence to help those who menstruate make informed choices regarding the potentially harmful substances in a number of different products used to absorb or collect menstrual blood. This FAQ is based on a search of peer-reviewed academic literature, manufacturer information and expert opinion. We focus on menstrual products such as tampons, disposable pads, menstrual cups and panty liners. We could find no studies on exposure to harmful ingredients in reusable pads, menstrual underwear or cloth, nor any referring to homemade products. This is an important gap in the data as it omits products which are often used in low- and middle income countries.

What are most menstrual products made of?

Products often have multiple ingredients. Commercial products are often made primarily from cotton or polyester (absorbent material) with additional substances to bind those materials, provide a waterproof barrier, assist with use (e.g. applicator, tampon string) and/or provide fragrance or mitigate odor. Here are a few examples:

Tampons: main ingredients are usually cotton and/or rayon with additional polyester and/or polypropylene components. May have plastic or cardboard applicators.

Disposable pads: main ingredients are usually cellulose, often with plastic to prevent leakage (Woeller et al., 2015). Recent news from Kenya revealed that a major menstrual product manufacturer may have been selling sub-standard products of unknown ingredients under well-known brand names (Gamonde, 2019; Daily Nation, 2019). There is, as yet, no research into the products and ingredients for disposable pads used by small enterprise or cottage industry.In addition to unknown substances in the ingredients, the materials may contain undesirable bacteria.

Menstrual Cups: usually made from medical-grade silicone, with some cheaper cups made from thermoplastic polymers (Kemikalieinspektionen, 2018).Medical grade silicone is hypoallergenic and does not react to chemicals or absorb bacteria, which makes it safe for use in menstrual cups.

Panty liners: often cotton, but with layers made from plastic. Glue used to hold the pad or liner in place may contain allergenic chemicals (Scranton, 2013).

Commercial washable pads: made from cotton and sometimes polyester; main concern would be if not made of certified organic or well-washed cotton could contain residues from dyes, pesticides or various treatments added to fabric. Research is needed as we could find little or no information on reusable pads .

Washable pads made at home or by cottage industry are often made from cotton or rags, but there is no research into the safety of the materials used .


What potentially harmful substances can be found?

It is beyond the scope of this FAQ to review all safety data of every known harmful substances in menstrual products. Below is an overview of the most common ones.

Glyphosate: Much of the cotton is genetically modified to withstand herbicides which contains glyphosate, a probable carcinogen;it is found an association between non-Hodgkin lymphoma (NHL) and glyphosate based on the available human evidence (Portier et al., 2016; Zhang et al., 2019 ).

Dioxins: by-product of cotton and wood pulp bleaching, can be a side product of the chemical process of bleaching ingredients for products. They are highly toxic, an endocrine disruptor, and carcinogen. They also can cause reproductive and developmental problems, and damage the immune system, (WHO, 2016).  Bleaching processes have been developed which result in less dioxin.

Phthalates: are common ingredient in fragrances. Menstrual products are often advertised as being ‘odour-free’, which in turn is an indicator that they contain fragrances (Scranton 2013, Kemikalieinspektionen 2018).

Volatile organic compounds (VOCs): A recent study indicates that surveyed menstrual pads contain VOCs (methylene chloride, toluene, and xylene) which are dangerous to human health. However, amounts measured were below the reference dose (RfD); daily absorption of toluene (VOC) from sanitary pad reached to the maximum of 38.4% RfD (Park et al., 2019). Long-term exposure to various VOCs may cause cancer and damage to the liver, kidneys or central nervous system (NIH, 2019).    


What are the potential health risks?

Scranton suggests that dioxins, furans, pesticide residues and unknown fragrance chemicals – found in both disposable pads and tampons – could be associated with cancer, reproductive health problems and/or hormonal disruptions. The vagina is self-cleansing and does not require fragrances or perfumes to clean it. Disposable pads, which contain adhesive chemicals such as methyldibromo glutaronitrile, have also been linked to allergic rashes (Scranton, 2013).

Phthalates used as plasticizer of polymers, chlorine compounds used as bleaching agents in disposable menstrual pads, as well as styrene, endocrine-disrupting chemicals (EDC), chloroform, and chloroethane which were also found in the disposable pads,  pose potential health hazards such as breast cancer, infertility, endometriosis for users because they are in prolonged close contact with the skin (WVE, 2014; Bae et al., 2018, Lynn, 2018).

Moreover, studies suggest that chemical workers who have prolonged exposure to carbon disulfide (used in the production of rayon tampons) and rayon in the process of production may experience changes in their menstrual cycles, breast cancer, increased incidence of spontaneous abortion, as well as other negative impacts on their neurologic, cardiovascular, gastrointestinal and immune systems (Hemminki et al.,1980; Zhou et al.,1988; Labrèche et al., 2010; Davidson, 2012), and also workers in textile factories due to exposure to synthetic fibres experienced higher risk of miscarriage (Wong et al., 2009).

In addition, due to the byproducts of combustion, menstrual products containing chlorine and polythene pose a health threat to waste collectors working in disposal areas. Disposable pads made of super absorbent polymers (SAP) additionally harm the health of waste collectors and cleaners who have to remove blockages from sewers and clean septic tanks when pads are thrown into toilets (Elledge et al., 2018).


Why are menstrual products different?

Menstrual products come into prolonged contact with genital and vaginal mucous membrane which is highly absorbent. This means that ‘Safe levels’ of chemicals may be different for menstrual products compared to food. In addition, one woman may use from 5,000 to 15,000 disposable menstrual products during her 35-40 reproductive years (WoMena, 2019). The presence of a potential harmful substance should be assessed not only by its quality, but also the exposure to different population groups (MedTech Europe, 2015).


What is the evidence of  harmful substances?

However, little research has been done to investigate the presence of substances with potential negative health consequences in menstrual products at unsafe levels, a recent study indicated disposable pads contained VOCs and phthalates though the amounts measured were different among the brands and were below the reference dose; daily absorption of toluene from disposable pad was of 38.4% reference dose since menstruators are exposed to various chemicals through various routes, consideration should be given to the risks of chemicals that are additionally absorbed from the disposable pad (Park et al., 2019).

In addition, a risk health assessment done by ANSES on the safety of the menstrual products (e.g. tampons, disposable pads, panty liners, and menstrual cups) revealed the presence of various chemical substances in very low concentration and without exceeding the health thresholds; the majority of these substances would come from contamination of raw materials or manufacturing processes (ANSES, 2018).Many of the earlier studies come from the United States and deal with dioxins in tampons, which are the most widely used menstrual product in the US (Scranton 2013).

DeVito and Schecter analysed four brands of tampons and concluded that, although they all contained dioxins, the levels were well below those considered safe for food, and therefore they did not pose a health risk (DeVito and Schecter, 2002). Other researchers arrived at similar conclusions (Scialli, 2001; Archer et al., 2005). The studies did not consider whether levels for foodstuffs are applicable to menstrual products.

Glyphosate has also been studied. For example, a report by the Swedish Chemicals Agency noted that although glyphosate was indeed found in the tampons, the levels were not considered harmful.

The glyphosate analysis was part of a 2018 study of 35 locally available menstrual products – tampons, disposable pads, panty liners and menstrual cups – by the Swedish Chemicals Agency. Tests were done for 62 different potentially dangerous chemicals. The study found 21 chemicals in the products, and there was enough information from other studies and standards to do a risk assessment for 18 of these compounds. Three could not be assessed due to a lack of information on their health effects. One product (a menstrual cup which did not indicate the country of manufacture but was labelled in Chinese) contained chemicals which could not be assessed with the tests available. The report concluded that the levels of substances were below the levels considered harmful. (Swedish Chemicals Agency, 2018).

It seems that the safety threshold levels were based on the assumption that 100% of the chemical would be absorbed, but any information on whether there should be a multiplier factor related to the number of products used over a menstruator’s lifetime could not be found.

In August 2018, the Danish Consumer’s Union published a test of seven different menstrual cups.  The conclusion was that all the brands of cups were generally free from unwanted chemicals although there was variation by brand in terms of presence of some minor findings of an unwanted phthalate and tar substances (PAHs);all were considered safe to use, and the Consumer’s Union concluded that menstrual cups were a good  alternative in terms of safety from problematic chemicals. A recommendation was made to boil the cups to ensure removal of any volatile compounds,no reference was made to the manufacturer’s printed recommendation to boil the cups (Müller, 2018).

We could find no further information regarding what happens to any harmful substances during disposal of any product (in particular those which are produced in high quantities and incinerated).  We discussed environmental concerns in a separate FAQ.


What is being done regarding consumer safety and menstrual products?

Menstrual products are classified as ‘medical devices’ in the United States, and ‘hygiene products’ or ‘general products’ in the European Union. This means manufacturers are not obliged to disclose ingredients or any test results (Elledge et al., 2018; Kaur, 2018). The US Federal Drug Administration guidance is that tampons should be free of dioxins and pesticide residue, but the recommendation is not mandatory, and testing shows that they do not comply (Scranton, 2013). We have not been able to do a full review of post-marketing surveys (e.g. MAUDE reports in the US) (US.FDA, 2019).

Since 1997, US Congress representative Carolyn Maloney has presented a bill to require testing and disclosure of menstrual product components. None of her proposals has passed. The latest iteration of the bill, presented in 2017, “requires [the National Institute of Health] to study [whether] the contaminants and substances used, such as dioxin, synthetic fibers, fragrances, dyes, and preservatives in feminine hygiene products [which] pose health risks to women who use the products or to the children of women who use the products during or before pregnancy.” (H.R. 2379 Robin Danielson Feminine Hygiene Product Safety Act of 2017, 2017; Maloney, 2015). Until more is known, it is recommended choosing unperfumed products which disclose ingredients, products made from organic cotton, or menstrual cups (Mercola, 2013, King, 2017).


Conclusions and recommendations

This topic has many data gaps, party because menstrual product manufacturing companies do not list all the ingredients in their products publicly and they have not been mandated to do so by governments. There are potentially harmful substances in products such as tampons and disposable pads, which this may also be true for other, untested products. Further, chemical exposure safety levels do not currently differentiate between exposure via consumption (as in food) or absorption (as in menstrual products), and neither the length of exposure to menstrual products over the reproductive lifespan nor to EDC seem to factor in. We could find no information regarding reusable pads of any material. Menstrual cups made of medical-grade silicone have been tested and found free of harmful substances, but like other products, findings vary by brand.

It is concerning that producers are not required to disclose ingredients or safety evaluations of their menstrual products, and variations in how these products are classified in different countries (e.g. as luxury items, cosmetics, medical devices, hygiene products, general products), complicating consumers’ ability to hold manufacturing companies to account.

WoMena is concerned that the standard for the setting levels of harmful substances does not discuss whether exposure levels differ between menstrual products and food.

Womena is also concerned by a lack of research into disposal, whether incineration, burying near water source, landfill, sewers etc.  (WoMena, 2019).

Moreover, due to the fact that the high absorption rate of the genitalia for chemicals, and the long-term exposure period demand a thorough investigation on the potential impact of the exposure to VOCs and phthalates (Park et al., 2019).

In order to eliminate or, if not possible, as much as possible reduce the presence of harmful chemical substances, in particular those with carcinogens, mutagens or reprotoxins (CMR), endocrine disruptors or skin sensitisers, it is recommended developing a more restrictive regulatory framework to limit the presence of CMR substances, as well as urging manufacturers to improve the quality of raw materials and revise certain manufacturing processes (ANSES, 2018).

It is suggested that, until better information is available, quality menstrual cup is a safer choice, or unperfumed pads or tampons made from disclosed ingredients and organically grown cotton. WoMena therefore recommends menstrual cups.



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